Front End Design of Personalized Medicine Facilities

According to a new article in Pharmaceutical Engineering, “The commercialization of personalized medicine has ushered in demand for a new type of facility—personalized medicine facilities—which can produce thousands of small-scale batches per year. Designing these personalized medicine facilities presents new challenges, and a different design approach is necessary.

Cyclic scheduling can produce high-quality models rapidly and aid collaborative design. A focus on room and zone availability and movements can prevent bottlenecks in corridors, gowning, and airlocks to streamline production.”

In this article, subject matter experts, Sean Tully and Tom Bannon, PM Group discuss:

• The differences between designing a bulk drug substance production facility and a large-scale personalized medicine facility
• How designers need to account for the large number of discrete movements and must allow adequate time in the production schedule for room and corridor cleaning.
• When faced with the challenge of designing scaled-out, personalized medicine facilities, how existing methods are a bottleneck to the design process
• The development of a modelling philosophy around cyclic scheduling, high-quality models can be produced rapidly
• Models that can be produced in an easy to comprehend format. Critically, without stakeholders needing to be familiar with complex software
• How by focusing on room and zone availability and movements, bottlenecks particular to personalized medicine facilities can be prevented.

Read more:

https://ispe.org/pharmaceutical-engineering/may-june-2024/front-end-design-personalized-medicine-facilities